Apoptosis Research

Useful list of apoptosis inducers and inhibitors and their references.

Very useful Apoptosis review page.

Cancer Research

Cancer Genome Anatomy Project: database of the genes responsible for cancer, N.I.H.

Cell & Stem Cell Biology Research

Informational resources for cellular and molecular biology.

Stem Cell Information. A National Institues of Health maintained site about resources, funding and policy concerning stemcells.

National Stem Cell Resource site, links to protocols, methods and terminology.

Human and Animal Cell Lines. A comprehensive database of characterized human and animal cell lines.

Cell signaling networks database for human cells; pathways are interactively represented by computerized graphics, NIHS, Japan.

ATCC catalog of cell lines including hybridomas that produce a broad spectrum of antibodies

Proteases and protease inhibitors, University of Tours, France.

Mike Clark’s Immunoglobulin Structure Home Page. This is a great site for extensive diagrams and 3D models of various Ig structures.

Cell Migation Informational Consortium, a wonderful collection of reviews, molecules and pathways.

A good informational site for the study of Angiogenesis.

Gateway to information, methods and definitions on Adhesion molecules of all kinds.

Excellent search database for cell markers and finding what markers are expressed on what celltype.

Cell Biology website references for students and teachers.

Wonderful table for ADAM proteins with links to the sequences.

ECM research information for all the ECM proteins (collagens, Fibronectin, laminins etc.).

Wonderful site for anything on human transporter proteins.

Review of the method of immunoprecipitation and discussion of it.

Excellent review of Integrin Signaling.

Cell Surface/CD Marker Resources

Comprehensive list of CD Markers and descriptions of function and tissue distribution (with staining images)

Excellent search database for cell markers and finding what markers are expressed on what celltype.

Excellent resource for FACS methods and protocols.

Disease & Diagnostic Resources

Extensive annotations of 鈥榟ot molecules鈥 that may play crucial roles in common diseases, Weizmann Institute.

GeneCards: a database of human genes, their products and their involvement in disease, Weizmann Institute

Positionally cloned human disease genes, N.I.H.

A wonderful information and methods site for research in virology.

Alzforum Alzheimer Resarch Forum Home Page. A very active site with many comparisons of antibodies against various Alzheimer related targets.

Huge resource of information on all kinds of neurobiology related diseases and pathology.

Identification of yeast genes whose mRNA levels are regulated by the cell cycle, Stanford.

Predictions of GalNAc O-glycosylation sites in mammalian proteins, Technical University of Denmark.

AMA鈥檚 site for CPT codes and information.

Gateways to Large Online Informational Resources

NCBI Homepage

Swiss-Prot Protein Knowledgebase. Search various protein databases including the NiceProt anaotated view of Swiss-Prot Database entries.

ExPASy Molecular Biology Server. Links to Databases, Tools and Software packages

The AfCS-Nature Signaling Gateway is a comprehensive resource for information about cell signaling, Alliance for Cell Signaling and the Nature Publishing Group.

Biomolecular Interaction Network Database serves full descriptions of interactions of proteins, nucleic acids and small molecules.

Cytokines online encyclopedia, University of Munich.

MEROPS the peptidase database information resource.

MRI atlas of mouse development online.

LocusLink provides a single query interface to curated sequence and descriptive information about genetic loci. It presents information on official nomenclature, aliases, sequence accessions, phenotypes, EC numbers, MIM numbers, UniGene clusters, homology, map locations, and related web sites.

Molecular Biology Shortcuts, links to molecular and cellular biology methods and databases.

Computational Biology and Informatics Laboratory at the University of Pennsylvania

Gateway to information, methods and definitions on Adhesion molecules of all kinds.

Huge assortment of informational biology related links.

Cell Migation Informational Consortium, a wonderful collection of reviews, molecules and pathways.

Wonderful site for anything on human transporter proteins.

Gateway to the WWW. Virtual Library

General Science Resources

On-Line Dictionary of Cell and Molecular Biology

Useful page detailing the accept names for various mammalian animals and animal sexes.

Biology website references for students and teachers.

A wonderful information and methods site for research in virology

Online atlas of mouse embryos.

Excellent review for fixation and fixation related issues.

Kimball鈥檚 biology online, excellent resource for all sorts of biological information.

Wonderful search engine for scientific information of all types.

Genome & Mutation Databases

GenBank, an annotated database of all publicly available DNA sequences, N.I.H.N.L.M.

Sequence database of long (>4 kb) human cDNAs, Kazusa DNA Research Institute.

Links to resources for expressed sequence tags analysis, University of Brescia.

Human Genome Project database, Toronto.

The human genomic research program, Sanger Center.

TIGR human gene index.

Human mitochondrial genome, Emory University.

The mouse genome, Jackson Laboratory.

Drosophila genome project, Berkeley.

C. elegans genome, Sanger Center.

S. cerevisiae genome, Stanford.

Completely sequenced bacterial genomes and the yeast genome, Universite Claude Bernard, Lyon.

Database of disease-causing mutations in tyrosine kinase domains, links to other mutation databases, University of Tampere.

Atlas of Genetics and Cytogenetics in Oncology and Haematology, dedicated to biological and molecular aspects of cancer and cancer-prone diseases.

Online Mendelian Inheritance in Man: catalog of human genes and genetic disorders, N.I.H.

Human Gene Mutation Database, Institute of Medical Genetics, Cardiff.

Online Mendelian Inheritance in Animals: catalog of animal genes and genetic disorders, University of Sydney

Cancer Genome Anatomy Project: database of the genes responsible for cancer, N.I.H.

Links to a number of locus specific mutation databases, N.I.H.

Positionally cloned human disease genes, N.I.H.

Immunohistochemistry Resources

This page contains our online collection of protocols in the fields of general histology, immunhistochemistry, immunofluorescence, in situ hybridization, antigen retrieval, and electron microscopy.

General guidelines for Immunostaining.

Excellent review for fixation and fixation related issues.

Excellent immunohistochemistry methods resource page with links to many, many protocols.

Knockout and Transgenic Mice

List of those genes which have been ablated in mice and the phenotypic effects of these knockouts.

Transgenic and targeted mutant animal database, Oak Ridge National Laboratory.

Source of mouse strains with transgenes, or with targeted or chemically-induced mutations, The Jackson Laboratory.

Neuroscience Research

Neural network predictions of phosphorylation sites in eukaryotic proteins, Technical University of Denmark.

Collaborative effort to build integrated, multidisciplinary models of neurons and neural systems, Yale University.

Alzforum Alzheimer Resarch Forum Home Page. A very active site with many comparisons of antibodies against various Alzheimer related targets.

Huge resource of information on all kinds of neurobiology related diseases and pathology.

Online and Literature Search Engines

Google Search Engine, particularly good for science and literature searching.

A very useful site for finding bioreach reagents comparing the various vendor offerings.

SciQuest. A useful search engine for finding a variety of science materials

Excellent reference search engine with links to journals and Medline.

NLM鈥檚 search service to citations in MEDLINE, with links to online journals and other related databases, N.I.H.

Free 鈥渁lerting鈥 service that scans daily updates to the NCBI, Medline and GenBank databases.

Effort to make the world’s scientific and medical literature freely accessible to scientists and to the public around the world.

Molecular, Proteomic/Genomic Tools

Proteins. A useful basic reference on protein structure and bonding.

Protein Calculator. A useful interface for calculating approximate molecular weight of any protein. Developed by Chris Putnam.

Pedor鈥檚 BioMolecular Research Tools. A collection of WWW links to information and services useful to molecular biologists.

PROW: Protein Reviews on the Web

EMBL-EBI HomePage-Links to Protein Sequence Analysis Databases

ExPASy Molecular Biology Server. Links to Databases, Tools and Software packages

PDB, repository for the processing and distribution of 3-D biological macromolecular structure data.

PIR-International Protein Sequence Database, a non-redundant, annotated database of protein sequences.

Biology Workbench, an integrated search, modeling and analysis platform that accesses all major protein and nucleic acid databases, University of Illinois

Excellent compendium of tools and resources for molecular biology and proteomics, University of California San Diego.

GenBank, an annotated database of all publicly available DNA sequences, N.I.H.N.L.M.

BLAST (Basic Local Alignment Search Tool), a set of search programs for identifying sequence similarities between protein and nucleotide sequences, N.I.H.N.L.M.

PredictProtein is a service for sequence analysis and structure prediction, Heidelberg.

Tool for analyzing the domain structure of protein sequences, PFAM consortium: Sanger Centre, Washington University, Karolinska Institute.

Genome Sequencing Center, Washington University

Online links to molecular sequence analysis tools for nucleotides and proteins, Whitehead Institute.

Computerized effort to model molecular interactions, Kyoto University.

Sequence database of long (>4 kb) human cDNAs, Kazusa DNA Research Institute.

Genomic sequences and tools, Max-Planck-Institut f. Biochemie Munich.

Molecular Biology Shortcuts, links to molecular and cellular biology methods and databases.

Links to resources for expressed sequence tags analysis, University of Brescia.

Wonderful set of helpful molecular biology tools and formula calculators.

Signal Transduction/Cytokine Research

The AfCS-Nature Signaling Gateway is a comprehensive resource for information about cell signaling, Alliance for Cell Signaling and the Nature Publishing Group.

Scansite predicts phosphorylation sites and specific domain-binding regions within proteins, MIT.

Neural network predictions of phosphorylation sites in eukaryotic proteins, Technical University of Denmark.

Analyses of protein kinases from human, yeast, worm and fly.

Signal transduction knowledge environment: resources and information on signal transduction, Science Magazine and Stanford University. Requires Subscription.

Protein Kinase Resource: the genetics, enzymology, and molecular properties of protein kinases, University of California San Diego.

TRANSPATH information system dedicated to gene-regulatory pathways.

Biomolecular Interaction Network Database serves full descriptions of interactions of proteins, nucleic acids and small molecules.

Open resource providing online maps depicting selected signaling pathways.

Cytokines online encyclopedia, University of Munich.

Links to cytokine, chemokine and related resources, Kumamoto University.

Nuclear Receptor Resource: a collection of databases on the nuclear receptor superfamily, Georgetown University.

Information system for G protein-coupled receptors.

Wnt gene homepage, Stanford.

Predictions of GalNAc O-glycosylation sites in mammalian proteins, Technical University of Denmark.

Cell signaling networks database for human cells; pathways are interactively represented by computerized graphics, NIHS, Japan.

Excellent review of Integrin Signaling.