Cancer Epidemiology Archives - Determinants /determinants/category/environment/cancer-epidemiology/ Ӱԭ University Tue, 29 Apr 2025 14:04:52 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 Surveillance of cancer risks for firefighters, police, and armed forces among men in a Canadian census cohort /determinants/2018/surveillance-of-cancer-risks-for-firefighters-police-and-armed-forces-among-men-in-a-canadian-census-cohort/ Sun, 17 Jun 2018 17:27:06 +0000 /determinants/?p=436 Firefighters, police, and armed services may be exposed to hazards such as combustion by‐products and shift work.The CanCHEC cohort linked 1991 census data to the Canadian cancer registry for follow up. Cox proportional hazards modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) to estimate risks for firefighter, police, or armed […]

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Surveillance of cancer risks for firefighters, police, and armed forces among men in a Canadian census cohort

June 17, 2018

Cancer Epidemiology

General

Health

Firefighters, police, and armed services may be exposed to hazards such as combustion by‐products and shift work.The CanCHEC cohort linked 1991 census data to the Canadian cancer registry for follow up. Cox proportional hazards modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) to estimate risks for firefighter, police, or armed forces compared to workers in other occupations. The cohort of 1 108 410 men included 4535 firefighters, 10 055 police, and 9165 armed forces. For firefighters, elevated risks were noted for Hodgkin’s lymphoma (HR: 2.89, 95%CI: 1.29‐6.46), melanoma (HR: 1.67, 95%CI: 1.17‐2.37), and prostate cancer (HR: 1.18, 95%CI: 1.01‐1.37). Police had elevated risks for melanoma (HR:1.69, 95%CI: 1.32‐2.16) and prostate cancer (HR:1.28, 95%CI: 1.14‐1.42). No significant associations were found for armed forces workers. Canadian firefighters, police, and armed services, may be at an increased risk of developing certain cancers. Results suggested that a healthy worker effect may influence risk estimates.

Harris A, Kirkham T, MacLeod J, Tjepkema M, Peters PA, & PA Demers. (2018) “Surveillance of cancer risks for firefighters, police and armed forces among men in a Canadian census cohort.” American Journal of Industrial Medicine.

 

 

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]]> Prostate cancer surveillance by occupation and industry /determinants/2018/prostate-cancer-surveillance-by-occupation-and-industry/ Thu, 01 Mar 2018 15:31:20 +0000 /determinants/?p=426 This is another article in a large series of papers done using the 1991 Canadian Census Health and Environment Cohort (CanCHEC), making use of the linkage to the Canadian Cancer Database (1969-2010). This series, some of which are profiled on our lab website, examines cancer risks by occupation and industry. This research is led by Paul […]

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Prostate cancer surveillance by occupation and industry

June 17, 2018

Cancer Epidemiology

General

Health

This is another article in a large series of papers done using the 1991 Canadian Census Health and Environment Cohort (CanCHEC), making use of the linkage to the Canadian Cancer Database (1969-2010). This series, some of which are profiled on our lab website, examines cancer risks by occupation and industry. This research is led by from the and the .

Abstract

As there are no well‐established modifiable risk factors for prostate cancer, further evidence is needed on possible factors such as occupation. Our study uses one of the largest Canadian worker cohorts to examine occupation, industry, and prostate cancer and to assess patterns of prostate cancer rates. The Canadian Census Health and Environment Cohort (CanCHEC) was established by linking the 1991 Canadian Census Cohort to the Canadian Cancer Database (1969–2010), Canadian Mortality Database (1991–2011), and Tax Summary Files (1981–2011). A total of 37,695 prostate cancer cases were identified in men aged 25–74 based on age at diagnosis. Cox proportional hazards models were used to estimate hazards ratios and 95% confidence intervals. In men aged 25–74 years, elevated risks were observed in the following occupations: senior management (HR = 1.12, 95% CI: 1.04–1.20); office and administration (HR = 1.19, 95% CI: 1.11–1.27); finance services (HR = 1.09, 95% CI: 1.04–1.14); education (HR = 1.05, 95% CI: 1.00–1.11); agriculture and farm management (HR = 1.12, 95% CI: 1.06–1.17); farm work (HR = 1.11, 95% CI: 1.01–1.21); construction managers (HR = 1.07, 95% CI: 1.01–1.14); firefighting (HR = 1.17, 95% CI: 1.01–1.36); and police work (HR = 1.22, 95% CI: 1.09–1.36). Decreased risks were observed across other construction and transportation occupations. Results by industry were consistent with occupation results. Associations were identified for white‐collar, agriculture, protective services, construction, and transportation occupations. These findings emphasize the need for further study of job‐related exposures and the potential influence of nonoccupational factors such as screening practices. ()

Citation

Sritharan J, MacLeod J, Harris S, Cole DC, Harris A, Tjepkema M, Peters PA, & PA Demers. (2018). “Prostate cancer surveillance by occupation and industry: the Canadian Census Health and Environment Cohort (CanCHEC).” Cancer Medicine. 7(4): 1468-1478.

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]]> Sedentary work and the risks of colon and rectal cancer by anatomical sub-site in the Canadian census health and environment cohort (CanCHEC) /determinants/2017/sedentary-work-and-the-risks-of-colon-and-rectal-cancer-by-anatomical-sub-site-in-the-canadian-census-health-and-environment-cohort-canchec/ Sat, 19 Aug 2017 02:56:44 +0000 http://spatialdeterminants.com/?p=212 M Pahwa, MA Harris, J MacLeod, M Tjepkema, PA Peters, PA Demers Cancer epidemiology 49, 144-151 Background Sedentary behaviour is a potential risk factor for colorectal cancer. We examined the association between sedentary work, based on body position, and colorectal cancer risk in Canadians. Methods A working body position category (a. sitting; b. standing and […]

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Sedentary work and the risks of colon and rectal cancer by anatomical sub-site in the Canadian census health and environment cohort (CanCHEC)

June 17, 2018

Cancer Epidemiology

General

Health

M Pahwa, MA Harris, J MacLeod, M Tjepkema, PA Peters, PA Demers
49, 144-151

Background

Sedentary behaviour is a potential risk factor for colorectal cancer. We examined the association between sedentary work, based on body position, and colorectal cancer risk in Canadians.

Methods

A working body position category (a. sitting; b. standing and walking; c. sitting, standing, and walking; d. other) was assigned to occupations reported by 1991 Canadian Census respondents based on national occupational counselling guidelines. Adjusted hazard ratios (HRs) and 95% confidence intervals (CI) were estimated for cancers of the colon (overall, proximal, and distal) and rectum in men and women newly diagnosed from 1992 to 2010.

Results

Compared to “sitting” jobs, men in occupations with “other” (non-sitting, −standing, or −walking) body positions had a weakly significant reduced colon cancer risk (HR = 0.93, 95% CI: 0.89, 0.98) primarily attributed to protection at the distal site (HR = 0.90, 95% CI: 0.84, 0.97). Men in “standing and walking” and “sitting, standing, and walking” jobs did not have significantly reduced colon cancer risks. No effects were observed for rectal cancer in men or colon and rectal cancer in women.

Conclusion

The two significant findings of this analysis should be followed-up in further investigations with additional information on potential confounders. Null findings for rectal cancer were consistent with other studies.

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